NPTE Plan

NPTE practice question: System Interactions

System InteractionsDifficulty 3/5

A patient taking warfarin reports a swollen, painful knee after a minor fall. What does this most likely represent?

  1. AAn acute meniscal tear requiring mechanical testing and treatment
  2. BReactive synovitis that will settle with ice and activity modification
  3. CA haemarthrosis requiring medical evaluation before joint mobilisation
  4. DA routine effusion that responds to compression and gentle exercise
Show answer and rationale

Correct: C. Anticoagulation makes bleeding into the joint likely after trauma. Haemarthrosis needs medical evaluation; manual techniques and aggressive exercise can worsen the bleed.

  • D — Assuming a benign effusion in an anticoagulated patient risks missing a haemarthrosis.
  • A — Mechanical testing would apply stress to a potentially bleeding joint.
  • B — Attributing swelling to synovitis without evaluation is unsafe under anticoagulation.

Concept being tested

8-10 scored items that exist only under Foundations for Evaluation, Differential Diagnosis and Prognosis. Multi-system presentations, medical red flags, medication effects on therapy and when to refer rather than treat. — 5% of the exam. Study guide for System Interactions.

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Primary references

  1. NPTE-PT Test Content Outline, effective January 2024 (v1.1) — Federation of State Boards of Physical Therapy (FSBPT) · primary · retrieved 2026-09-22, verified 2026-09-22
Last reviewed: 2026-10-07Reviewed by: Dr. Andrew Sullivan, PT, DPT, OCS, Physical therapy curriculum & clinical examination reviewHow we verify facts